Extensive research is being conducted
Many studies are conducted which are all looking very closely at the roles of CB one and CB two cannabinoid receptors and especially the part which they play in things such as digestion, diet, and energy metabolism. History tells us that people have been making use of cannabis for a very long time. Long before the ancient people have mastered the art of writing. The natural plant has been used for cloth and for rope. Furthermore, the flowers, leaves, and roots were used for physical healing. It was also used in various rituals and ceremonies. The seeds of the plant were a food source. As early as the Neolithic period various parts of the cannabis plant had been used for one thing or another. There are indications that cannabis could have been one of the first agricultural crops which was harvested by mankind. This is estimated to have happened over 12,000 years ago. It should be remembered that agriculture is not something which occurs naturally. It is something which has been invented by humans and which was one of the foundations for modern civilization. Back then the agricultural process was certainly one of the most important developments of that time. This provided human beings with many benefits because of their expanded diet.
There are now indications that many of the current chronic metabolic disorders could have developed because of a mismatch between high caloric diets and ancient genes. These problems start at the same time as the introduction of agriculture. Today chronic metabolic disorders are a worldwide health problem. The evolutionary process which extends over millions of years and during which the genetic changes have happened very slowly was apparently disrupted when the hunter-gatherer diet was replaced by carbohydrate-rich foods. It is now suspected that there is a strong correlation between the human diet and the endocannabinoid system. These systems are important in order to understand the problems which people have today with things such as diabetes and obesity. The body’s own endocannabinoid system is a prehistoric biological signaling network which is responsible to regulate many of the physiological processes. This includes things such as glucose metabolism, intestinal function, and stress responses. According to studies, a malfunctioning endocannabinoid system seems to be causing difficulty for the bowl and metabolic pathologies. It is also the direct cause of many other diseases.
The function of the endocannabinoid system
The endocannabinoid system is complex and it plays an important role in bodily function. Especially important is the CB1 and CB2 receptors which are playing an important role in energy metabolism, diet, and digestion. Among the various mammals, CB one receptors are located in the central nervous system and in the brain. They can also be found in the enteric nervous system as well as in the taste buds. Studies have shown that the psychoactive component in marijuana known as THC can boosts appetite by attaching itself to the CB one receptor. Apparently, CB one receptors can have a contradictory impact on food intake. It can improve essential nourishment but also cause metabolic imbalance. Studies have shown that it is the CB one receptor which will trigger the suckling instinct in newborn babies. There is a substantial amount of arachidonic acid in mother milk which is known as an important building block of the brain’s own marijuana-like compounds which is known as anandamide and 2AG. Researchers have discovered that these endogenous cannabinoid compounds will bind themselves to the same cell receptors known as CB one and CB two. That will facilitate many of the marijuana-like effects.
Foods containing arachidonic acid
Arachidonic acid is present in things such as meat, eggs, and dairy products. When consumed it will increase endocannabinoid levels in various parts of the body. It has been found to be very important as far as brain development in babies is concerned. Ancient humans had to make a living in what could be described as a wilderness. That lifestyle resulted in a lot of physical exertion. Survival did not come easy and they had to rely on hunting and gathering for their daily food. There were many challenges such as microbial infection, famine, and confrontations with other predators. All of this was typical of a lifestyle before the advent of agriculture. The lifestyle of that early humans required them to consume nutrient-rich and energy dense foods. Their strenuous daily activities and large brains depended on a special diet. The CB one receptor has been important in order to stimulate appetite and to improve their sense of smell. It would also help to make it easier to survive after a difficult day which might have been full of trauma and stress. The CB one receptor would be actively involved in restoring homeostasis as well as helping humans to deal with negative memories. It would also help to eliminate anxiety which might have an effect on the central nervous system. Whenever the CB one receptor is activated this can help to decrease energy expenditure and also to increase energy intake. This is accomplished by managing neural pathways.
A healthier lifestyle
Because of the extremely active lifestyle which was led by hunter-gatherers their diet had not lead to obesity, cardiovascular disease or any kind of metabolic problems. Although this high-fat diet has been perfect for our ancestors, things have changed significantly with our modern-day cultivated food. With the current system of carbohydrate farming, the body had to adapt. Today we have diets which are over processed, over-starched and over sweetened and this is leading to many problems. Things such as sugar, carbs, alcohol, grain as well as corn syrup are consumed. The reality is that something which has started as the foothold of civilization had degenerated into something which is threatening human existence. In those early days’ carbohydrates was is essential for social development and cognitive abilities. Now they have become a metabolic stress factor which is resulting in many problems for people. Studies have revealed epidemiological evidence which is now pointing toward a pandemic diet-induced glucose toxicity because people are consuming too much sugar.