Government clinical trial authorizations are currently discussing CBD and research on Uterine fibroids. So is this something worth discussing? Considering this piece of research, it may be well worth gathering some more information.
What are Uterine fibroids?
This is a condition where abnormally but mostly noncancerous polyps are located in the uterus and this is then referred to as Uterine fibroids. This is a condition which will affect a fertile woman, in other words, those with the ability to bear children. It is frequently seen by medical practitioners how a woman can develop uterine fibroids which will be of different sizes.
It is possible that they might develop some which is very tiny and which will not the result in any physical deformities. It is also possible that very large uterine fibroids may develop which can result in deformation. Several symptoms may become apparent such as severe menstrual bleeding, abdominal pain and extensive menstrual cycles may be another symptom of uterine fibroids.
It is important to get a professional diagnosis. This might result in a pelvic examination or occasionally an ultrasound. It can happen that the woman may only have a solitary experience with uterine fibroids but there is also another woman who can suffer from this condition numerous times.
On the positive side, it rarely happens that any of these growths develop into full-scale cancer. There is also very little chance of uterine cancer.
Our bodies are wonderfully created
It is now a well-known fact that the body has its own cannabinoid receptors which are located inside the tissue of sex steroid hormones. There are several studies underway to look at the possibility that CBD therapy can be used for the treatment of sex hormone tumors. There are already many research results which have been published which showed that the endocannabinoid system is able to restrict the progression and the movement of various tumors which are discovered within sex hormones.
It has been suggested during extensive studies that cannabinoid compounds such as CBD can actually be useful in the effective treatment of malignancies, uterine fibroids as well as a range of other hormone disorders simply by stimulating the ECS. When endocannabinoids and sex steroid hormones are used together there is a strong possibility of the ECS been successful in order to restrain cellular accumulation and growth inside of tumors.
The endocannabinoid system
The ECS and its receptors are located right through the human body. You will find them in the digestive system, in the hormone-releasing glands, in human bones, in their reproductive organs, in the lungs, brain, connective tissues, hair, and skin. It should be understood that the endocannabinoid system is a very complex internal signaling arrangement that has an impact on multiple metabolic pathways.
It is made up of transmembrane endocannabinoid receptors and various proteins. It’s interesting to see that one of the primary ingredients of cannabis is THC or tetrahydrocannabinol. This substance has a remarkable effect on the body’s own ECS and the way it can interact with the CB-1 and CB-2 receptors. Many studies have already been done with THC and its equivalents especially in things such as palliative treatments where they are known to inhibit tumor cell growth.
This has led to increasing interest in the very important role which THC can play in the modulation of the endocannabinoid system especially as far as a cancer treatment is concerned.
What are endocannabinoids?
This is unsaturated fatty acid derivatives which are considered by researchers to be synthesized as they are needed. This is done by phospholipid precursors which is present in the plasma membrane. Another theory is that they might also be synthesized and stored in what is known as intracellular lipid droplets.
When needed, they will be released from those locations. One of the best-known forms of endocannabinoids is anandamide which was the first endogenous ligand which has been coupled with cannabinoid receptors. They are also the most intensively investigated endocannabinoid.
Looking at Uterine leiomyomata or fibroids
This is a very common and mostly benign tumor which will affect the uterine muscle. This will happen to older women. It often happens that these tumors can cause pelvic pain, pressure, and bleeding. The hormone estrogen will be required in order to allow fibroids to grow and therefore there are therapies that decrease estrogen levels which can cause fibroids to become smaller and in this way many of the symptoms can be controlled.
The problem is that such medications can only be used for brief periods of time. There are also many unacceptable side effects such as hot flushes. And this is why the majority of women who are suffering from symptomatic fibroids will undergo surgery to have the problem removed. Many women will only have the fibroids removed but some will also choose to have the uterus removed by having a hysterectomy.